At least 30 people have been killed in Israeli airstrikes on three houses in southern Gaza's Rafah, medics said on Monday.
The recent casualties come as Egyptian and Qatari mediators were expected to hold a new round of cease-fire talks with Hamas leaders in Cairo.
In Gaza City, in the north of the Gaza Strip, Israeli warplanes struck two houses, killing at least four people and wounding several people, health officials said.
The strikes on Rafah, where more than one million people are seeking refuge from months of Israeli bombardment, took place hours before Egypt was expected to host leaders of the Palestinian resistance group Hamas to discuss prospects for a cease-fire agreement with Israel.
The Israeli military said it was checking the report.
Israel has vowed to eradicate Hamas, which controls Gaza, in a military operation that has killed more than 34,000 Palestinians, 66 of them in the past 24 hours, according to Gaza's health authorities. The war has displaced most of the 2.3 million population and laid much of the enclave to waste.
The conflict was triggered by the Oct. 7 Hamas incursion which caused the deaths of around 1,200 people and 253 people were taken hostage, according to Israeli tallies.
An assault on Rafah, which Israel claims is the last Hamas stronghold in the Gaza Strip, has been anticipated for weeks but foreign governments and the United Nations have expressed concern that such action could result in a humanitarian disaster given the number of displaced people crammed into the area.
On Sunday, Hamas officials said a delegation led by Khalil al-Hayya, the group's deputy Gaza chief, would discuss a cease-fire proposal handed by Hamas to mediators from Qatar and Egypt, as well as Israel's response. Mediators, backed by the United States, have stepped up their efforts to conclude a deal.
Two Hamas officials who spoke to Reuters did not disclose details of the latest proposals but a source briefed on the talks told Reuters that Hamas is expected to respond to Israel’s latest truce proposal delivered Saturday.
The source said this included an agreement to accept the release of fewer than 40 hostages in exchange for releasing Palestinians held in Israeli jails and to a second phase of a truce that includes a "period of sustained calm" – Israel’s compromise response to a Hamas demand for a permanent cease-fire.
After the first phase, Israel would allow free movement between south and north Gaza and a partial withdrawal of Israeli troops from Gaza, the source said.
A senior Hamas official told Reuters the Monday talks in Cairo will take place between the Hamas delegation and the Qatari and Egyptian mediators to discuss remarks the group has made over the Israeli response to its recent proposal.
"Hamas has some questions and inquires over the Israeli response to its proposal, which the movement received from mediators on Friday," the official told Reuters.