Yemeni Houthis faced a new wave of attacks as American and British forces carried out strikes against at least 18 targets on Saturday.
The latest barrage of airstrikes comes following weeks of unrelenting attacks on Red Sea shipping by the Iran-backed rebels.
The strikes "specifically targeted 18 Huthi targets across eight locations in Yemen" including weapons storage facilities, attack drones, air defense systems, radars and a helicopter, a joint statement said.
It was co-signed by Australia, Bahrain, Denmark, Canada, the Netherlands and New Zealand, who gave unspecified "support" to the new round of strikes, the second this month and fourth since the rebels began their attacks on ships in the region.
"The Huthis' now more than 45 attacks on commercial and naval vessels since mid-November constitute a threat to the global economy, as well as regional security and stability, and demand an international response," the statement added.
Houthi-run Al-Masirah television reported "a series of raids on the capital Sanaa," while AFP correspondents in the rebel-controlled city in western Yemen said they heard several loud bangs.
"The United States will not hesitate to take action, as needed, to defend lives and the free flow of commerce in one of the world's most critical waterways," Pentagon chief Lloyd Austin said in a separate statement after the strikes.
"We will continue to make clear to the Houthis that they will bear the consequences if they do not stop their illegal attacks, which harm Middle Eastern economies, cause environmental damage, and disrupt the delivery of humanitarian aid to Yemen and other countries."
Houthi military spokesman Yahya Saree was defiant, vowing in a social media statement that the rebels would "confront the American-British escalation with more qualitative military operations against all hostile targets in the Red and Arab Seas."
The U.K. Ministry of Defence said four Royal Air Force Typhoon FGR4s targeted "several very long-range drones, used by the Houthis for both reconnaissance and attack missions," on Saturday, at a site northeast of Sanaa.
Saturday's operation comes after several merchant vessels were struck this week in the region, including the fertilizer-filled Rubymar, whose crew had to abandon ship after it was hit several days ago and began taking on water.
British maritime security agency UKMTO reported another attack on an unspecified ship near the port of Djibouti on Saturday night, saying there had been an "explosion in close proximity to the vessel, no damage is reported to the vessel and there are no injuries to the crew."
"Vessel is proceeding to next port of call," it added in a bulletin.
Apart from the joint operations with Britain, the United States has also carried out unilateral strikes against Houthi positions and weaponry in Yemen, and has downed dozens of missiles and drones in the Red Sea.
Earlier Saturday, U.S. Central Command (CENTCOM) announced that an American Navy vessel had shot down an anti-ship ballistic missile "launched into the Gulf of Aden from Iranian-backed Houthi controlled areas of Yemen."
The missile "was likely targeting MV Torm Thor, a US-Flagged, owned, and operated chemical/oil tanker," CENTCOM said on X, formerly Twitter.
U.S. forces on Friday also shot down three attack drones near commercial ships in the Red Sea and destroyed seven anti-ship cruise missiles on land, CENTCOM said.
The Houthis say they are targeting Israel-linked vessels in support of Palestinians in Gaza, which has been ravaged by Israel's brutal war that killed over 29,600 people.
Following previous U.S. and U.K. strikes, the Houthis declared American and British interests to be legitimate targets as well.
The Houthis will "persist in upholding their religious, moral and humanitarian duties toward the Palestinian people, and their military operations will not stop unless the aggression stops and the siege on the Palestinian people in the Gaza Strip is lifted," military spokesman Saree said.
Anger over Israel's devastating campaign in Gaza – which began after the unprecedented Oct. 7 Hamas incursion – has grown across the Middle East, stoking violence involving Iran-backed groups in Lebanon, Iraq, Syria and Yemen.