Israel continued its brutal offense on southern Gaza's Rafah Wednesday as cease-fire negotiations to end the seven-month conflict resumed in Cairo on Wednesday.

Despite international objections, Israel sent tanks into Rafah on Tuesday and seized the nearby crossing into Egypt that is the main conduit for aid into the besieged Palestinian territory.

The White House condemned the interruption to humanitarian deliveries, with a senior U.S. official later revealing Washington had paused a shipment of bombs last week after Israel failed to address U.S. concerns over its Rafah plans.

The Israeli military said hours later it was reopening another major aid crossing into Gaza, Kerem Shalom, as well as the Erez crossing.

But the U.N. agency for Palestinian refugees, UNRWA, said the Kerem Shalom crossing – which Israel shut after a rocket attack killed four soldiers on Sunday – remained closed.

It came after a night of heavy Israeli strikes and shelling across Gaza. Media footage showed Palestinians scrambling in the dark to pull survivors, bloodied and caked in dust, out from under the rubble of a Rafah building.

"We are living in Rafah in extreme fear and endless anxiety as the occupation army keeps firing artillery shells indiscriminately," said Muhanad Ahmad Qishta, 29.

"Rafah is a witnessing a very large displacement, as places the Israeli army claims to be safe are also being bombed," he told Agence France-Presse (AFP).

Al-Ahli hospital said a strike on an apartment in devastated Gaza City killed seven members of the same family and wounded several other people.

'Catastrophic'

An emergency doctor working in Rafah and neighboring Khan Younis said that with humanitarian access compromised, the health situation was "catastrophic."

"The smell of sewage is rife everywhere," said Doctor James Smith. "It's been getting worse over the course of the last couple of days."

The conflict was triggered by the Oct. 7 Hamas incursion of southern Israel, abducting about 250 people and killing around 1,200.

Israel has killed more than 34,500 Palestinians in its genocidal war, according to Gaza’s local health officials, caused widespread destruction and plunged the territory into an unprecedented humanitarian crisis.

Talks aimed at agreeing a cease-fire resumed in Cairo on Wednesday "in the presence of all parties," Egyptian media reported.

A senior Hamas official said the latest round of negotiations would be "decisive."

"The resistance insists on the rightful demands of its people and will not give up any of our people's rights," he told AFP on condition of anonymity because he was not authorized to speak publicly on the negotiations.

The official had previously warned it would be Israel's "last chance" to free the scores of hostages still in militants' hands.

Mediators have failed to broker a new truce since a weeklong cease-fire in November saw 105 hostages freed, the Israelis among them in exchange for Palestinian prisoners held by Israel.

Incursion condemned

Qatar, which has been mediating between the two sides, appealed "for urgent international action to prevent Rafah from being invaded and a crime of genocide being committed."

The African Union condemned Israel's Rafah incursion while Russia warned it would destabilize an area sheltering more than 1 million people and called on Israel to strictly observe international humanitarian law.

A Palestinian analyst said Israel's seizure of the Rafah crossing could be an attempt to create new facts on the ground, or a bid to "sabotage the truce talks."

"The takeover is also a symbol shown to the world that Hamas is not in control anymore," said Mkhaimar Abusada, of Al-Azhar University in Gaza.

Israel's seizure of the Palestinian side of the Rafah crossing came after Hamas said it had accepted a truce proposal – one Israel said was "far" from what it had previously agreed to.

Israeli Prime Minister Benjamin Netanyahu described the operation as "a very important step" in denying Hamas "a passage that was essential for establishing its reign of terror."

Hours later, a senior U.S. administration official speaking on condition of anonymity said Washington had "paused one shipment of weapons last week" after Israel failed to address its concerns over the Rafah incursion, which the United States has vocally opposed.

The shipment had consisted of more than 3,500 heavy-duty bombs, the official said.

It was the first time President Joe Biden had acted on a warning he gave Netanyahu in April that U.S. policy on Gaza would depend on how Israel treated civilians.

Aid pier completed

The U.S. official said Washington was "especially focused" on the use of the heaviest 2,000-pound (907 kilograms) bombs "and the impact they could have in dense urban settings."

The Pentagon, meanwhile, said the U.S. military had completed construction of an aid pier off Gaza's coast, but weather conditions meant it was currently unsafe to move it into place.

Defense Minister Yoav Gallant said Israel might "deepen" its Gaza operation if negotiations failed to bring the hostages home.

"This operation will continue until we eliminate Hamas in the Rafah area and the entire Gaza Strip, or until the first hostage returns," he said.

Egypt and Qatar have taken the lead in the truce talks, with Hamas saying Monday it had told officials from both countries of its "approval of their proposal regarding a cease-fire."

Hamas member Khalil al-Hayya told the Qatar-based Al Jazeera news channel the proposal involved a complete Israeli withdrawal from Gaza, the return of displaced Palestinians and a hostage-prisoner exchange, with the goal of a "permanent cease-fire."

Netanyahu's office called the proposal "far from Israel's essential demands," but said the government would still send negotiators to Cairo.