U.N. Secretary-General Antonio Guterres warned Tuesday that humanity is facing an "existential crisis" due to the relentless destruction of life-sustaining nature.

"Every year, we see temperatures climbing higher. Every day, we lose more species. Every minute, we dump a garbage truck of plastic waste into our oceans, rivers and lakes. Make no mistake. This is what an existential crisis looks like," the secretary-general told delegates to the UN's COP16 biodiversity summit in Cali, Colombia.

The 16th so-called Conference of Parties (COP16) to the U.N.'s Convention on Biological Diversity (CBD) must make progress on the creation of monitoring and funding mechanisms to achieve 23 goals agreed in Canada two years ago to "halt and reverse" nature destruction.

Themed "Peace with Nature," the summit has been bogged down in disagreement about modalities of funding.

Negotiators are also split on how best to share the profits of digitally sequenced plant and animal genetic data – used in medicines and cosmetics – with the communities they come from.

Delegates have no time to waste.

There are only five years left to achieve the 23 U.N. targets, which include placing 30 percent of land, water and ocean under protection by 2030.

"Every day, we lose more species. Every minute, we dump a garbage truck of plastic waste into our oceans, rivers and lakes. Make no mistake. This is what an existential crisis looks like," Guterres told delegates.

A report issued by nature watchdogs said Monday that only 17.6% of land and inland waters, and 8.4% of the ocean and coastal areas are protected and conserved.

And an update of the International Union for Conservation of Nature's red list of threatened animals and plants found that more than one in three species of tree are at risk of extinction worldwide.

These include thousands that provide humans with timber, medicine, food and fuel.

More than 46,000 plant and animal species out of the more than 166,000 assessed are now threatened with extinction.

'More money'

Guterres said humans must make the switch from "plundering... to preserving" nature's bounty. Continued destruction would only increase "hunger, displacement, and armed conflicts."

"Nature is life. And yet we are waging a war against it," the U.N. secretary-general told COP16 delegates.

"No country, rich or poor, is immune to the devastation inflicted by climate change, biodiversity loss, land degradation and pollution. These environmental crises are intertwined," he added.

To this end, he urged the 196 countries signed up to the U.N. biodiversity convention to act on the commitments made two years ago when they adopted the Kunming-Montreal Global Biodiversity Framework.

This means adopting detailed national biodiversity protection plans, only 36 of which have been submitted to date.

Furthermore, "finance promises must be kept and support to developing countries accelerated," said Guterres, calling for new public and private pledges.

So far, countries have made about $400 million in commitments to the Global Biodiversity Framework Fund (GBFF), including pledges of $163 million announced this week by Austria, Denmark, France, Germany, New Zealand, Norway, the United Kingdom, and the Canadian province of Quebec.

The Kunming-Montreal framework determined that countries must mobilize $20 billion per year by 2025 from rich nations to help developing ones. The GBFF is just part of this funding.

Of the $20 billion goal, $15 billion a year was reached for 2022, according to the OECD.

COP16 has attracted a record 23,000 registered delegates and some 1,200 journalists to Cali, according to organizers.

Tens of thousands of activists and residents have flocked to its so-called "green zone" set up for cultural activities, demonstrations and celebrations.

More than 10,000 police and soldiers were deployed to safeguard the event which had received threats from a Colombian guerrilla group. No incidents have been reported.

On Tuesday and Wednesday, Guterres is joining the heads of state of Colombia, Armenia, Guinea-Bissau, Haiti and Suriname, as well as 115 government ministers and 44 deputies.

The ministers will hopefully "help us make movement" on some outstanding issues, said CBD spokesman David Ainsworth.

The COP16 summit runs until Friday.