Spanish superstar Rafael Nadal survived a freak injury when he accidentally bloodied his nose with his own racquet to reach the U.S. Open third round Thursday.

Nadal defeated Italy's Fabio Fognini 2-6, 6-4, 6-2, 6-1 but only after suffering the bizarre injury when leading 3-0 in the fourth set.

The four-time champion, and holder of a men's record 22 Grand Slam titles, was hurt when his racquet bounced back off the court as he stretched for a ball and hit him squarely on the nose.

The 36-year-old Australian and French Open champion dropped his racquet to the Arthur Ashe Stadium floor and sprinted to the sidelines where he lay on his back with his nose bloodied.

He required a medical timeout to have the wound tended before resuming with a bandage across the bridge of his nose.

"I was a little bit dizzy and it was a little bit painful," said Nadal, who said he had suffered a similar injury in the past caused by a golf club.

Nadal said despite being a set and 4-2 down, he was happy to have recovered after coming into the tournament still worried by the abdominal injury he suffered at Wimbledon.

"I had to play better. It was one of the worst starts ever for me," he said.

"It has been tough in the last month so I knew these kind of things can happen."

Heartbreak for Williams sisters

For the first time since 2018, Serena and Venus Williams revived a partnership that has brought them 14 doubles titles in the majors.

However, their hopes of collecting a third crown in New York were dashed in a 7-6 (7/5), 6-4 defeat to Czech pairing Linda Noskova and Lucie Hradecka.

The loss leaves 40-year-old Serena free to focus on what is widely expected to be the final singles campaign of her landmark 27-year career before retirement.

On Friday, the 23-time Slam singles winner will face Australia's Ajla Tomljanovic for a place in the fourth round.

Serena and her 42-year-old sister went down fighting, clawing back from 1-4 down in the second set before the Czech pair steadied the ship.

"I'm still in shock," said Hradecka.

Meanwhile, Victoria Azarenka triumphed against Marta Kostyuk 6-2, 6-3 in a match dominated by bitter exchanges over the conflict in Ukraine.

Last week, Belarusian star Azarenka was axed from an exhibition event aimed at raising money for the war-ravaged country.

Ukraine's Kostyuk had refused to take part in protest at the presence of Azarenka, who she has criticized for a perceived failure to condemn the invasion of her home country.

Belarus is a close ally of Russia and has allowed Moscow to use its territory to launch attacks into Ukraine.

The tension between the two was evident at the end of their tie on Court 17 with Kostyuk offering just a touch of racquets instead of the customary post-match handshake.

"How did it make me feel? It's not the most important thing in the world right now," said Azarenka.

No handshake

Kostyuk, the 20-year-old world No. 65, said a handshake would not have been appropriate.

"I genuinely wanted to warn her that I'm not going to shake her hand," she said.

"She never came up to me personally to tell me her opinion, what she thinks (about the war)."

Away from the controversy, world No. 1 and French Open champion Iga Swiatek cruised into the third round with a 6-3, 6-2 win over 2017 champion Sloane Stephens.

Paula Badosa, the fourth seed and potential semifinal opponent of Swiatek suffered another miserable return to the city of her birth.

The Spaniard's failure to get beyond the second round will stretch for another year after losing 6-7 (5/7), 6-1, 6-2 to Petra Martic of Croatia.

Sixth seed Aryna Sabalenka, a semifinalist in 2021, came back from 1-5 down in the second set and saved two match points to defeat Kaia Kanepi, 2-6, 7-6 (10/8), 6-4.

China will have four women in the last 32 for the first time at a Slam after Zheng Qinwen defeated Anastasia Potapova and Yuan Yue got the better of Irina-Camelia Begu.

Zhang Shuai and Wang Xiyu had already booked their spots in the next stage.

Alcaraz through

Spanish teenager Carlos Alcaraz dug deep to save 13 of 14 break points to defeat Federico Coria of Argentina.

World number four Alcaraz, a quarter-finalist in 2021, went through 6-2, 6-1, 7-5 on the back of 46 winners.

Cameron Norrie and Dan Evans reached the third round giving Britain four men in the last 32 in New York for the first time since 1933.