Lowly Getafe ended Real Madrid's 11-match undefeated run in the La Liga with a 1-0 win on Sunday while a COVID-19 hit Barcelona scraped to victory away at Mallorca.

Coach Carlo Ancelotti said Real Madrid was "still on holiday" following the surprise defeat, its first in three months. However, it gives fresh hope to the beleaguered chasing pack in Spain, after Eder Militao's early error allowed Turkish forward Enes Ünal to score the winner at the Coliseum Alfonso Perez.

"We were on holiday for an extra day," said Ancelotti afterward. "The team was not the same team that played before Christmas – less commitment, less concentration.

"We didn't deserve to lose but we ended up with a defeat that could be a wake-up call."

Barcelona, in the meantime, was without eight first-team players who had tested positive for COVID-19 last week while a further six were out through injury or suspension.

Xavi Hernandez said Saturday it was "crazy" the game had to go ahead, with Jordi Alba, Ousmane Dembele and Gavi among those infected, while Sergio Busquets was suspended and Pedri, Ansu Fati and Memphis Depay injured.

But a patched-up Barcelona team climbed to fifth, just a point behind Atletico Madrid, after Luuk de Jong's header proved the difference in a 1-0 win over Mallorca.

Atletico Madrid claimed the fourth spot after beating the high-flying Rayo Vallecano 2-0 to leapfrog Rayo, with Angel Correa scoring both of Atletico's goals.

Atletico and Barca are still 14 and 15 points behind Real Madrid respectively but Sevilla in second will be only five adrift of the leader, with a game in hand, if it wins at Cadiz on Monday.

Madrid has taken command of the Spanish title race after a superb run of form that included 10 consecutive wins and 15 matches without defeat, its last loss coming at Espanyol on Oct. 3.

But Ancelotti's side was woefully out of sorts in its first outing of 2022 and, aside from a brief spell in the first half, struggled really even to threaten the Getafe goal.

Eden Hazard came on at halftime but again failed to shake his team into life while Karim Benzema was unusually quiet upfront. Madrid certainly missed the penetration of Vinicius Junior, who was absent after testing positive for COVID-19.

"To say we were still on holiday isn't a criticism, it's the same thing that I've said to the players," Ancelotti said.

"We accept responsibility because the coach was maybe still on holiday as well. We are still top, so we look forward."

Getafe lost eight games in a row earlier in the season but came in on the back of an upturn in form under Quique Sanchez Flores, having gone five games unbeaten, including a pair of wins over Cadiz and Osasuna.

Ünal gave them the lead in the ninth minute after the usually dependable Militao was caught napping. The Brazilian went to clear on the edge of his own area but instead took an extra touch, engaging in a tussle with Ünal, who robbed the ball and finished past Thibaut Courtois.

Hazard and Marcelo both came on at halftime but neither made much of an impact, with Hazard unable to muster a single attempt on goal. Benzema had a shot blocked, Casemiro saw a half-volley saved and Mariano Diaz headed over, but Getafe deserved its victory.

De Jong has been linked with leaving Barcelona this month but it was his goal that secured a crucial victory over Mallorca, the Dutchman heading in Oscar Mingueza's cross at the back post to make it four games unbeaten now under Xavi.

Barca also needed a stunning, reaction save from Marc-Andre ter Stegen, whose right arm denied Jaume Costa from volleying in an equalizer in injury-time.

Atletico had suffered four consecutive defeats in La Liga for the first time ever under Simeone but Correa's double ensured it bounced back against Rayo, who drop to sixth.